William A. Haseltine, PhD
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Books
Better Eyesight: What You And Modern Medicine Can Do To Improve Your Vision.
From the leading edge of biotech and healthcare innovation, Dr. William A. Haseltine and Kim Hazel MPH come forth with a revolutionary resource – “Better Eyesight: What You And Modern Medicine Can Do To Improve Your Vision.” This trailblazing book maps out the vanguard of eye care technologies and treatments, offering new hope to those affected by vision issues. Better Eyesight is a valuable resource for anyone interested in eye care, whether you are a healthcare professional or just someone who wants to learn more about eye health and wellness. “Better Eyesight: What You and Modern Medicine Can Do to Improve Your Vision” illuminates modern advances in ophthalmology, including brain implants and gene therapy, and offers in-depth information on treatments such as stem cell and gene therapies for retinal disorders, laser photocoagulation, and more.![CAR T - ACCESS Health Book Cover - Neon](https://www.williamhaseltine.com/wp-content/uploads/2024/03/cover1.png)
The COVID-19 Textbook: Science, Medicine, and Public Health
The COVID-19 Textbook: Science, Medicine, and Public Health explores every facet of SARS-COV-2, giving the reader an understanding of what is needed to control the spread of the virus, prevent and manage its pathological effects, as well as mitigate the impact of future pandemics. Each chapter is authored by leading global experts in the field and includes topics such as molecular biology, epidemiology, pathogenesis, immunology, diagnosis, and the latest prevention and treatment approaches. Edited by renowned educator and medical researcher Dr. William A. Haseltine, physician-researcher, and chronic fatigue syndrome expert Dr. Roberto Patarca, it includes detailed references in every chapter, allowing easy access to comprehensive primary data.
![ACCESS Health Book Cover](https://www.williamhaseltine.com/wp-content/uploads/2024/05/COVID-textbook.jpg)
CAR T: A New Cure for Cancer, Autoimmune and Inherited Disease
For most of modern medicine, cancer drugs have been developed the same way: by designing molecules to treat diseased cells. Chimeric Antigen Receptor T cell therapy, commonly referred to as CAR T therapy, is a revolutionary cell-based immunotherapy treatment that breaks this mold. A patient’s cells are transformed through genetic engineering and reinfused into the bloodstream, allowing the cells to identify and eliminate their targets better than they naturally can. For many patients, this translates to a long-term remission or cure. As an early pioneer in cell therapies using dendritic macrophages to treat prostate cancer, Dr. William Haseltine now sees the immense potential for CAR T. In his latest book, he describes how CAR T cell therapy works, the potential and possibilities of integrating mRNA technology, current uses to treat cancer and ongoing efforts that adapt this system to treat other illnesses, including heart disease, HIV/AIDS and rheumatoid arthritis.![CAR T - ACCESS Health Book Cover - Neon](https://www.williamhaseltine.com/wp-content/uploads/2023/11/CAR-T-Cover.jpeg)
Ending Hepatitis C: A Seven-step Plan for a Successful Eradication Program
Just a few years ago, Egypt and the United States had approximately the same number of people infected with chronic hepatitis C. Today, Egypt has been declared virtually free of the disease, while the opioid crisis is driving an increase in hepatitis C infection rates in the United States In their latest book, Dr. William Haseltine and Kaelyn Varner, MPH, discuss lessons from the success of Egypt’s 100 Million Healthy Lives initiative and how those programs can be modified and scaled in countries of all economic levels. He identifies the seven universal traits that can be adapted to eliminate any endemic disease, such as HIV, malaria and tuberculosis, in any country. The book also provides a detailed account of the history, transmission, impact on the body, available treatments, and the ongoing efforts to eliminate this disease.![Ending Hepatitis C](https://www.williamhaseltine.com/wp-content/uploads/2023/11/Hep-C-Cover.jpg)
Viroids & Virusoids: Nature’s Own mRNA
Messenger RNA (mRNA) has become a key therapeutic modality. Propelled into the spotlight by the COVID-19 pandemic, vaccines are only the tip of the iceberg: there’s an mRNA revolution on the horizon. But long before mRNA was thought of as a potential therapeutic drug, nature devised its own transmissible messenger RNA: viroids and virusoids. By studying the mechanisms of these small, naked RNAs, we can learn to increase the efficiency of mRNA. In his latest book, Dr. William Haseltine explores the world of viroids and virusoids in full detail: from their potential origins in the primordial soup —roughly three to four billion years ago— to the diseases they cause and everything in between. Each step along the way is ripe with implications for fields as diverse as biomedicine and agriculture. In addition to highlighting potential futures for mRNA, the book also discusses how virusoids can help us understand and address the fatal human disease of hepatitis D.![Viroids & Virusoids: Nature’s Own mRNA](https://www.williamhaseltine.com/wp-content/uploads/2023/09/71rtRsqohHL._SY522_.jpg)
The Future of Medicine: Healing Yourself: Regenerative Medicine
“Dr. William Haseltine first coined the term Regenerative Medicine in 1999, since then, the field has rapidly expanded. By studying our natural healing abilities, we are unlocking new ways to regenerate tissues, improve outcomes, and enhance the quality of life for people across the world. Whether it involves cell, gene, or protein therapies, or cutting-edge biomechanical interventions, regenerative medicine is revolutionizing the healthcare landscape as we know it. This book provides an overview of some of the most exciting, emerging areas of Regenerative Medicine, including DNA, antibody, and cellular therapies and organoid and transplant innovations.![Regenerative Medicine](https://www.williamhaseltine.com/wp-content/uploads/2023/09/Regenerative-Medicine-front-cover-updated.png)
Monoclonal Antibodies: The Once and Future Cure for Covid-19
“Dr. William Haseltine first coined the term Regenerative Medicine in 1999, since then, the field has rapidly expanded. By studying our natural healing abilities, we are unlocking new ways to regenerate tissues, improve outcomes, and enhance the quality of life for people across the world. Whether it involves cell, gene, or protein therapies, or cutting-edge biomechanical interventions, regenerative medicine is revolutionizing the healthcare landscape as we know it. This book provides an overview of some of the most exciting, emerging areas of Regenerative Medicine, including DNA, antibody, and cellular therapies and organoid and transplant innovations.![antibodies](https://www.williamhaseltine.com/wp-content/uploads/2023/09/antibodies-cover.png)
A Family Guide to Long Covid
“One in five adults infected with Covid-19 are now experiencing Long Covid symptoms. As more people are affected and awareness of the condition grows, many are searching for answers to their questions about Long Covid. What is Long Covid? How is it different from a Covid infection? What are the symptoms? Who is affected? How do I talk to my doctor about Long Covid? How can I advocate to get the care I need? Infectious disease expert, Dr. William Haseltine answers these questions and more in A Family Guide to Long Covid (ACCESS Health Press, July 2022). Continuing in the accessible question and answer style of the best-selling, A Family Guide to Covid the book provides straightforward answers about all aspects of Long Covid with equal measures of clarity and compassion. A Family Guide to Long Covid: Questions and Answers covers everything you need to know about Long Covid from symptoms and diagnosis to treatment and how different populations are affected. It serves as a resource that patients can use to advocate for their care and a guide for those who want to understand, prepare, and protect their families and friends.”![Omicron Cover](https://www.williamhaseltine.com/wp-content/uploads/2022/07/to-long-covid.jpeg)
Omicron: From Pandemic to Endemic
Covid-19 has challenged and upended many common notions around viral infection. The Omicron variant is likely the most infectious virus since the 1918 influenza pandemic with over 200 million cases currently confirmed worldwide. As many as a third of the global population may have been infected with the Omicron variant, considering unreported cases and asymptomatic carriers. In his latest book, bestselling author William A. Haseltine and co-author Griffin McCombs offers a detailed analysis of how the Omicron variant evolved to evade our best defenses and provides a roadmap for how we might protect ourselves against future variants. Omicron: From Pandemic to Endemic (ACCESS Health Press, April 2022) collects insights from the latest research on the entire family of Omicron variants and explains the lessons that we need to implement in our public health and medical practices going forward. While many governments and citizens alike are growing weary of protective Covid-19 measures, Haseltine argues that this is not the time to let our guard down. The increasing transmissibility of the Omicron variant demonstrates the immense capacity for evolution by this virus. In terms of lethal potential, SARS-CoV-2 sits on a knife’s edge, one unlucky point mutation away from becoming substantially more dangerous.![Omicron Cover](https://www.williamhaseltine.com/wp-content/uploads/2022/03/Omicron.jpg)
Natural Immunity
Understanding our natural immunity to the SARS-CoV-2 virus is critical to understanding the Covid-19 pandemic and serves as a guide to what more we can do to protect ourselves. The natural immune system is what equips the body with the tools necessary to counter new threats from the microbial world and prevent severe disease. Only when these natural protections fail do we succumb to critical illness or death. How natural immunity functions has eluded our understanding—until now. This book collects insights from a fast-growing body of scientific research on the next frontier of pandemic control, not just for Covid-19 but existing and future infectious diseases. We now find ourselves in a uniquely challenging stage of the pandemic, without a long-lasting vaccine and facing a virus that evolves rapidly to become more transmissible and to defeat our best attempts at prevention and treatment. Haseltine argues that one way forward is to develop drugs that strengthen our natural immune defenses and keep vulnerable populations protected and healthy against existing and future variants. The book maps out how the body mobilizes its natural defenses against SARS-CoV-2. It also describes the virus’s extensive set of countermeasures. Strengthening the natural immune system and devising means to thwart the virus’s countermeasures opens a golden path to prevention and treatment of Covid-19.![Natural Immunity Cover](https://www.williamhaseltine.com/wp-content/uploads/2022/03/Layer-177.jpg)
CV-PTSD
In CV-PTSD: What It Is and What To Do About It, bestselling author William A. Haseltine gives us a name for the trauma we have experienced throughout the pandemic, both individually and collectively: Covid Related Post Traumatic Stress Disorder (CV-PTSD). In addition to outlining the shape of our shared experience, the book also lays out a comprehensive road map to help us plot a course to rebuild our societies, better and healthier than they were before./ Each chapter of the book explores the effects of the pandemic on different groups, such as schoolchildren, parents, healthcare workers, and caregivers. Taken together, the work is an urgent call to action for policymakers, healthcare leaders and patients themselves to recognize the symptoms of our shared experience and to find new opportunities to rebuild society more completely and compassionately than before. CV-PTSD is a Living eBook, updated regularly with new information as it unfolds.![CV-PTSD Cover](https://www.williamhaseltine.com/wp-content/uploads/2021/07/CV-PTSD.jpg)
Science as a Superpower
When you think about superheroes, what comes to mind? Muscle-bound men and women adorned in capes or hi-tech armor? Superhuman abilities like flying or x-ray vision? It’s unlikely you thought of people in white lab coats looking through microscopes. But in real life, science is the most powerful superpower in the world. Think about it. Scientists have used their powers to make the once impossible happen: cure diseases, extend human life, feed the world, and bring us to outer space and beyond. They are, indeed, modern-day superheroes, saving and improving millions of lives. Dr. William Haseltine discovered the power of science at an early age. And now in his latest book, Science as a Superpower: My Lifelong Fight Against Disease and the Heroes who Made it Possible, he shares his love of science with the hope of inspiring young people to pursue a life in science and someday make their own contributions to improve human life. Woven throughout are stories of his work with some of recent history’s biggest scientific heroes, and of his many successes (and failures) as he learned how to harness the superpower that is science to build a successful—and deeply impactful—career of his own./![Science as a Superpower Cover](https://www.williamhaseltine.com/wp-content/uploads/2021/06/ScienceAsASuperpower.jpg)
Variants!
As the world moves into the second year of the Covid-19 pandemic, SARS-CoV-2 variants are now the fundamental issue at the root of many of our questions — Will the vaccines work? Will we need new shots each year? Will the pandemic end or can we expect a renewed surge of Covid-19 cases every year, like we see with the flu? Understanding virus variation is critical to understanding how the pandemic will unfold and how Covid-19 may continue to affect our global economy, our societies, and all of us individually. Will the current decline in new infections in the United States, for example, be permanent or a case of seasonal population immunity? These are the questions and issues at the heart of a new book by William A. Haseltine, PhD, Variants! The Shape-Shifting Challenge of COVID-19.My Lifelong Fight Against Disease
“Place this book at the top of your list. You will be inspired to make an impact on the world, with a remarkable guide to help show you the path.”
Sanjay Gupta, MD
Associate Professor of Neurosurgery, Emory; Chief Medical Correspondent, CNN Anticipating a career in medicine, Dr. William A. Haseltine was in his first weeks of graduate studies at Harvard when a legendary physician-scientist offered this advice: “You can do more for human health through science than you ever could as a doctor.” That advice hit him “like a thunderbolt”—and he took it. Since then, Dr. Haseltine has helped combat cancers, worked to contain the HIV/AIDS pandemic and unlocked the power of the human genome to develop dozens of new pharmaceutical cures. His discoveries in molecular biology and genomics, amplified through his counsel at the highest levels of government and in the public eye, have improved the health and lives of millions of people around the world. For the first time, Dr. Haseltine tells his life story—which is still unfolding—in My Lifelong Fight Against Disease, including facing devastating public health crises such as the COVID-19 pandemic, and highlighting exhilarating moments of medical discovery. In writing the story of his wide-ranging career, Dr. Haseltine’s goals are simple: to encourage the next generation to make their own significant contribution to human life, and for all readers to appreciate science as a humanistic enterprise. A compulsively readable and fast paced insider’s account of some of the most brilliant medical breakthroughs in modern history, My Lifelong Fight Against Disease is a candid, evocative and ultimately revelatory exploration into what it means to make science your life.“...an elegantly recounted story of a singular life studded with achievements. An erudite, illuminating account of a scientist’s remarkable journey.”
—Kirkus Reviews
“This gripping autobiography is at once a study in the development of a scientific mind infused with humanist commitment and a candid revelation of a complex and many sided personality. Readers will get to know great scientists, political figures, activists and above all the author himself, whose careers in molecular biology research and biopharmaceutical entrepreneurship have been of immense benefit to humankind.”
—Leo J. O’Donovan, S.J., President Emeritus, Georgetown University
“This compelling personal and professional story offers a superbly insightful analysis of what it will take for humanity to keep combatting increasingly complex health challenges and their devastating impacts. A life and career guided by a purpose to improve the health and well being of people everywhere is a legacy that gives hope.”
—Michelle Williams, Dean of the Faculty, Harvard T.H. Chan School of Public Health
“A timely, moving and inspirational account of the difference that a curious man can make in the world. He combines his powerful personal story with easy-to-read explanations of his tussles with medical science, and thrilling accounts of the political battles he faced.”
—Gillian Tett, Chair Editorial Board and Editor-at-Large, The Financial Times
“…a timely account of how one individual can impact global health, especially related to viruses… Readers will find this dramatic, self-reflective autobiography an entertaining and enlightening antidote to today's healthcare news.”
—Starred Blue Ink Review
“Enthusiasm in embracing the public context of science is all too rare in the science community. Bill models this in a joyful way, inspiring others to relish science and public engagement. This book is an instant classic!”
—Mary Woolley, President and CEO, Research!America
“A fascinating tale of growth and discovery of a medical scientist who thinks both deeply and broadly.”
—Alfred Sommer, MD
Dean Emeritus and Professor, Johns Hopkins Bloomberg School of Public Health
”My Lifelong Fight Against Disease is a fascinating memoir from one of the greatest scientists of our time.”
★★★★★ Clarion Review
“Readers will be swept along by the excitement of discovery, the urgency of breakthrough treatment, the impact of policy and the thrill of success. I can well imagine future leaders in health science looking back on this book as formative to their own journeys.”
—Brian Greene, Director, Columbia Center for Theoretical Physics; Co-founder and Chairman, World Science Festival
“Place this book at the top of your list. You will be inspired to make an impact on the world, with a remarkable guide to help show you the path.”
—Sanjay Gupta, MD, Associate Professor of Neurosurgery, Emory; Chief Medical Correspondent, CNN
Press
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Scientists are sure that a person can live forever. There's only one problem
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A Secret Factor Accelerates Aging, Scientists Say. The Clue Could Help Us Conquer Death.
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These States Have the Highest Number of COVID, Flu and RSV Cases Right Now—Is Yours on the List?
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Covid Commentaries: A Chronicle of a Plague
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After a lifetime spent in science, medicine, and pursuing better public health, Dr. Haseltine is once again logging eighteen-hour days battling a new and still somewhat unknown disease. His opinions on the course of the pandemic are sought regularly by major broadcast news networks and print media. The COVID Commentaries is a collection of Dr. Haseltine’s writings, research, and interviews on COVID-19.
Writings
Extending Telomere Length? A Look At Current Strategies (Posted on Wednesday, August 21, 2024) In the quest to unlock the secrets of aging and longevity, telomeres have emerged as key players. These protective caps at the ends of our chromosomes play a critical role in cellular aging. With each cell division, telomeres shorten, ultimately leading to cell death. But there are various budding strategies ... read more |
New Insights Into Aging: Not All Telomeres Are The Same (Posted on Tuesday, August 13, 2024) Telomeres, the protective caps at the ends of our chromosomes, act much like the plastic tips of shoelaces, preventing our DNA from fraying and sustaining its genetic integrity. However, as cells divide, these telomeres shorten, ultimately leading to cellular aging and dysfunction. This connection between telomere length and aging ... read more |
A New Target to Boost Cancer Immunotherapy: LAG-3 (Posted on Tuesday, August 6, 2024) Emerging research suggests that cancer therapies such as checkpoint inhibitors could be advanced by targeting a new protein. The protein, known as lymphocyte activation gene-3 or LAG-3, may prove particularly useful in improving patient responses to existing cancer treatments. Killing Cancer with Checkpoint Inhibitors Checkpoint inhibitors are an anticancer drug that indirectly ... read more |
How Cancer Immunotherapy Checkpoint Inhibitors Work (Posted on Monday, July 29, 2024) Skin cancers, lung cancers, lymphomas—though these cancers affect different parts of the body, they can all be treated with one of the latest therapies medicine has to offer: checkpoint inhibitors. This family of anticancer drugs can treat over 25 different types of advanced tumors and can be combined with other ... read more |
Cancer Therapy And The Intestinal Microbiome (Posted on Tuesday, July 23, 2024) A study published in Nature suggests a variation in responses to a cancer immunotherapy called checkpoint inhibitors may be due—at least in part—to a patient’s intestinal microbiome. Turning to the Intestines There are other similar reports that paint a connection between the microbiome—the collection of microorganisms ... read more |